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Misao is a fairly skilled ninja from the Oniwabanshu clan of ninja clan previously based in Edo. Her weapons of choice are the kunai. Misao is about sixteen years old when she is first introduced, though she appears younger.
According to Nobuhiro Watsuki, Misao’s character was initially a combination of Kamiya Kaoru and Myojin Yahiko: upon her introduction into the story, she acts somewhat childish and innocent. However, as the story progresses, she becomes more mature and empathetic without losing her cheerful attitude. Misao is short-tempered, but also free-spirited and energetic. She is loyal and strong-willed and will fight for what she believes in.