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Zegers began his performing career at an early age, appearing in commercials. His first film role was at the age of 7, in a small role in Michael J. Fox comedy Life With Mikey (1993). Subsequently, he appeared in many supporting roles, including a guest appearance on the TV series, The X-Files, playing a young stigmatic child. He had the starring role in Air Bud (1997), about a basketball-playing dog. In the years following, Zegers appeared in three of the film’s sequels, as well as a similar genre film, MVP : Most Valuable Primate, which featured a hockey-playing chimp.
Between 1997 and 2004, Zegers had starring or co-starring roles in many low-budget Canadian and horror films including Komodo (1999). He also appeared in the short-lived American television series, Titans co-starring Yasmine Bleeth, in 2000, for which he was personally chosen by producer Aaron Spelling. Zegers also worked with Bleeth in the 1999 movie It Came From the Sky.
After appearing in the remake of Dawn of the Dead, he had a major role in the Academy Award-nominated independent film, Transamerica (2005), co-starring Felicity Huffman. Zegers’s performance as the bisexual street hustling son of a male-to-female transsexual was praised by several critics, and he won the 2006 Cannes Film Festival Chopard Award, which is given to promising young actors1